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There are several matches for 'long-chain fatty acid--CoA ligase'.
Please select one from the list below and press Continue to proceed.
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8349 matches
showing page 1 of 418
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organism
protein
1)
Homo sapiens
ACSBG1 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
ACSBG1; Catalyzes the conversion of
fatty
acids
such as
long
-
chain
and very
long
-
chain
fatty
acids
to their active form acyl-
CoAs
for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated
fatty
acids
; Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily.
[a.k.a. ENST00000560817.5, 23205, hBG1]
2)
Homo sapiens
ACSBG2 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
ACSBG2; Catalyzes the conversion of
fatty
acids
such as
long
chain
and very
long
-
chain
fatty
acids
to their active form acyl-
CoAs
for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated
fatty
acids
. Has increased ability to activate oleic and linoleic
acid
. May play a role in spermatogenesis.
[a.k.a. NM_001321384.1, PRTD-NY3, ACSBG2-207]
3)
Homo sapiens
SLC27A4 -
Long
-
chain
fatty
acid
transport protein 4; Involved in translocation of
long
-
chain
fatty
acids
(LFCA) across the plasma membrane. Appears to be the principal
fatty
acid
transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-
CoA
ligase
activity for
long
-
chain
and very-
long
-
chain
fatty
acids
(VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-
CoA
. Prevents light-induced degeneration of rods and cones (By similarity); [...]
[a.k.a. NP_005085, R-HSA-804914, Solute carrier family 27 member 4]
4)
Homo sapiens
SLC27A1 -
Long
-
chain
fatty
acid
transport protein 1; Mediates the ATP-dependent import of
long
-
chain
fatty
acids
(LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-
CoA
ligase
activity for
long
-
chain
and very-
long
-
chain
fatty
acids
. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane- associated multimeric protein complex to trap and draw
fatty
acids
towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or trigl [...]
[a.k.a. ENST00000600277, R-HSA-804914, ENST00000599380.5]
5)
Homo sapiens
ACSL5 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
5; Catalyzes the conversion of
long
-
chain
fatty
acids
to their active form acyl-
CoAs
for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate
fatty
acids
from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated
fatty
acids
with a preference for C16-C18 unsaturated
fatty
acids
(By similarity). It was suggested that it may also stimulate
fatty
acid
oxidation (By similarity). At the villus tip of the crypt-villus axis of the small [...]
[a.k.a. R-HSA-556833, HPA007162, ENST00000354655]
6)
Homo sapiens
ACSL6 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
6; Catalyzes the conversion of
long
-
chain
fatty
acids
to their active form acyl-
CoA
for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in
fatty
acid
metabolism in brain and the acyl-
CoAs
produced may be utilized exclusively for the synthesis of the brain lipid; Belongs to the ATP-dependent AMP-binding enzyme family.
[a.k.a. UPI0003EAF834, C9JPA5, ACSL6-214]
7)
Homo sapiens
ACSL3 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
3; Acyl-
CoA
synthetases (ACSL) activates
long
-
chain
fatty
acids
for both synthesis of cellular lipids, and degradation via beta- oxidation. Required for the incorporation of
fatty
acids
into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Both isoforms exhibit the same level of activity (By similarity).
[a.k.a. ENST00000264415, O95573, ENST00000392066.7]
8)
Homo sapiens
ACSL1 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
1; Catalyzes the conversion of
long
-
chain
fatty
acids
to their active form acyl-
CoAs
for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate. Preferentially activates arachidonate than epoxyeicosatrienoic
acids
(EETs) or hydroxyeicosatrienoic
acids
(HETEs) (By similarity); Belongs to the ATP-dependent AMP-binding enzyme family.
[a.k.a. B7Z452, XP_016863376.1, XM_011531742]
9)
Homo sapiens
ACSL4 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
4; Catalyzes the conversion of
long
-
chain
fatty
acids
to their active form acyl-
CoA
for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially activates arachidonate and eicosapentaenoate as substrates. Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose- stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion. Belongs to the ATP-dependent AMP-binding enzyme family.
[a.k.a. UPI000016A488, ACSL4-202, NM_022977]
10)
Homo sapiens
SLC27A3 - Solute carrier family 27 member 3; Has acyl-
CoA
ligase
activity for
long
-
chain
and very-
long
-
chain
fatty
acids
. Does not exhibit
fatty
acid
transport activity (By similarity).
[a.k.a. ENST00000484014, UPI00005E26F0, Q5K4L6]
11)
Mus musculus
Acsbg1 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
ACSBG1; Catalyzes the conversion of
fatty
acids
such as
long
-
chain
and very
long
-
chain
fatty
acids
to their active form acyl-
CoAs
for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity). Can activate diverse saturated, monosaturated and polyunsaturated
fatty
acids
.
[a.k.a. Acyl-CoA synthetase bubblegum family member 1, Q99PU5, ENSMUST00000138315]
12)
Mus musculus
Acsbg2 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
ACSBG2; Catalyzes the conversion of
fatty
acids
such as
long
chain
and very
long
-
chain
fatty
acids
to their active form acyl-
CoAs
for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated
fatty
acids
. Has increased ability to activate oleic and linoleic
acid
. May play a role in spermatogenesis.
[a.k.a. ENSMUSG00000024207, ENSMUST00000043062.4, 6.2.1.3]
13)
Mus musculus
Slc27a4 -
Long
-
chain
fatty
acid
transport protein 4; Involved in translocation of
long
-
chain
fatty
acids
(LFCA) across the plasma membrane. Appears to be the principal
fatty
acid
transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-
CoA
ligase
activity for
long
-
chain
and very-
long
-
chain
fatty
acids
(VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-
CoA
. Prevents light-induced degeneration of rods and cones. Belongs to the [...]
[a.k.a. ACSVL4, CCDS15858.1, BB144259]
14)
Mus musculus
Slc27a1 -
Long
-
chain
fatty
acid
transport protein 1; Mediates the ATP-dependent import of
long
-
chain
fatty
acids
(LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-
CoA
ligase
activity for
long
-
chain
and very-
long
-
chain
fatty
acids
. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw
fatty
acids
towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or trigly [...]
[a.k.a. XP_030099440, ENSMUST00000034267, ENSMUST00000212111.1]
15)
Mus musculus
Acsl6 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
6; Catalyzes the conversion of
long
-
chain
fatty
acids
to their active form acyl-
CoA
for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity). Plays an important role in
fatty
acid
metabolism in brain and the acyl-
CoAs
produced may be utilized exclusively for the synthesis of the brain lipid (By similarity).
[a.k.a. ENSMUST00000064690.9, NM_001033598, NM_001033599.1]
16)
Mus musculus
Acsl5 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
5; Catalyzes the conversion of
long
-
chain
fatty
acids
to their active form acyl-
CoAs
for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity). ACSL5 may activate
fatty
acids
from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). It was suggested that it may also stimulate
fatty
acid
oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAI [...]
[a.k.a. ENSMUST00000224337.1, ENSMUST00000043150, ENSMUST00000163443]
17)
Mus musculus
Acsl3 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
3; Acyl-
CoA
synthetases (ACSL) activates
long
-
chain
fatty
acids
for both synthesis of cellular lipids, and degradation via beta- oxidation (By similarity). ACSL3 is required for the incorporation of
fatty
acids
into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins) (By similarity). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Both isoforms exhibit the same level of activity [...]
[a.k.a. ENSMUST00000035779, AK161708, ENSMUST00000035779.14]
18)
Mus musculus
Acsl1 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
1; Catalyzes the conversion of
long
-
chain
fatty
acids
to their active form acyl-
CoAs
for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity). Preferentially uses palmitoleate, oleate and linoleate (By similarity). Preferentially activates arachidonate than epoxyeicosatrienoic
acids
(EETs) or hydroxyeicosatrienoic
acids
(HETEs); Belongs to the ATP-dependent AMP-binding enzyme family.
[a.k.a. ENSMUSP00000106001, AC138367, AK149406]
19)
Mus musculus
Acsl4 -
Long
-
chain
-
fatty
-
acid
--
CoA
ligase
4; Catalyzes the conversion of
long
-
chain
fatty
acids
to their active form acyl-
CoA
for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially activates arachidonate and eicosapentaenoate as substrates. Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion (By similarity). Belongs to the ATP-dependent AMP-binding enzyme family.
[a.k.a. BC016416, NM_001033600.1, Acsl4-203]
20)
Mus musculus
Slc27a3 - Solute carrier family 27 member 3; Has acyl-
CoA
ligase
activity for
long
-
chain
and very-
long
-
chain
fatty
acids
. Does not exhibit
fatty
acid
transport activity.
[a.k.a. S27A3_MOUSE, AC145082, Acsvl3]
8349 matches
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